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Can premature ejaculation be treated?
Yes. Premature ejaculation is highly treatable. Many men improve with behavioral techniques, medication, counseling, or a combination of these approaches.
Does Dapoxetine work for premature ejaculation?
Yes. The research concludes that dapoxetine meaningfully improves control over ejaculation and increases the time to ejaculation compared to a placebo. It was also found to be generally safe and well tolerated, supporting its use as an effective treatment option.
Are SSRI medications used to treat premature ejaculation?
Yes. Certain Selective Serotonin Reuptake Inhibitors (SSRIs) such as sertraline, paroxetine, and fluoxetine are prescribed off-label because they delay ejaculation. They are usually taken daily and require medical supervision.
Selective serotonin reuptake inhibitors, or SSRIs, are often the first medical option used to treat premature ejaculation. In the United States, no medication is specifically approved for this condition. However, drugs such as fluoxetine, paroxetine, sertraline, citalopram, escitalopram, and clomipramine are frequently prescribed off-label and have been shown to help in both primary and secondary cases. These medications work by blocking the serotonin transporter, which increases serotonin levels at the synapse and helps delay ejaculation.
Can erectile dysfunction medications help?
In men who have both erectile dysfunction and premature ejaculation, medications such as sildenafil or tadalafil may improve confidence and erection quality. They are not considered primary treatment for PE alone.
The eight-week study found that while there were no significant improvements in IELT or VTS-ELT scores, sildenafil produced meaningful benefits in other areas. Men reported greater self-confidence, better perceived control over ejaculation, and higher overall sexual satisfaction. It also shortened the time needed to achieve a second erection after ejaculation.
Doctor Trusted Premature Ejaculation Prescription Treatment Options
There is currently no FDA-approved medication specifically for premature ejaculation. Still, doctors commonly prescribe certain drugs off-label to manage its symptoms. Our urology-experts find these treatments helpful, noting that they can help men last longer during intimacy, gain better control over orgasm, and feel more confident. Depending on the situation, these medications might be prescribed daily or as needed, and they can be used on their own or alongside other therapies.
Premature Ejaculation
Dapoxetine is a short-acting selective serotonin reuptake inhibitor (SSRI) used to treat premature ejaculation. Unlike traditional antidepressants, it’s taken only when needed, usually one to three hours before sexual activity. It works by increasing serotonin levels in the brain, which can help delay ejaculation and improve control. Side effects may include nausea, dizziness, headache, or sleep disturbance. It should be used under medical supervision, especially if combined with other medications that affect serotonin.
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Premature Ejaculation
Sertraline is another SSRI that can be used off-label to manage premature ejaculation. Like paroxetine, it increases serotonin levels, which helps extend the time to ejaculation and improve sexual control. It is usually taken daily, though some treatment plans may involve on-demand use before sexual activity. Results may take one to two weeks to become noticeable with regular dosing. A healthcare provider should guide dosing and discontinuation to reduce the risk of unwanted effects.
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Premature Ejaculation
Paroxetine is a selective serotonin reuptake inhibitor (SSRI) that is often prescribed off-label to treat premature ejaculation. It works by increasing serotonin levels in the brain, which can help delay ejaculation and improve control during sex. Among SSRIs, paroxetine is considered one of the more effective options for this purpose. It can be taken daily or, in some cases, a few hours before sexual activity, depending on a doctor’s recommendation. Benefits may take several days to a few weeks to become noticeable with daily use.
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Erectile Dysfunction
Sildenafil is a well-known medication used to treat erectile dysfunction, but it can also play a helpful role in managing premature ejaculation (PE). By improving blood flow to the penis, sildenafil helps men achieve and maintain a firmer erection, which can reduce performance anxiety and increase confidence during sex. For some men, this improved control and reduced stress can lead to longer-lasting intercourse. While sildenafil is not specifically approved as a primary treatment for PE, it may be prescribed alone or alongside other therapies when both erection issues and early ejaculation are concerns.
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Erectile Dysfunction
Tadalafil is another medication commonly prescribed for erectile dysfunction that may also support men dealing with premature ejaculation. Its longer duration of action, often lasting up to 36 hours, allows for greater flexibility and less pressure around timing, which can help reduce anxiety-related early ejaculation. By promoting consistent blood flow and stronger erections, tadalafil may help improve sexual confidence and overall performance. In cases where PE occurs alongside erectile difficulties, tadalafil can be part of a broader treatment plan. A healthcare provider can determine whether it’s appropriate based on individual health history and needs.
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Understand the basics of Premature Ejaculation
What is premature ejaculation?
Premature ejaculation (PE) is a common sexual health condition in which ejaculation happens sooner than desired, either before or shortly after penetration, with little control. Doctors typically describe it as ejaculation within about one minute of penetration in lifelong cases, or a significant reduction in time compared to previous experience, along with difficulty delaying ejaculation and personal distress.
How common is premature ejaculation?
Premature ejaculation is one of the most common male sexual concerns. Studies suggest that up to 20–30% of men experience it at some point in their lives. It can affect men of all ages.
What causes premature ejaculation?
Premature ejaculation can result from psychological, biological, or combined factors. Psychological contributors include performance anxiety, stress, depression, and early conditioning toward rapid climax. Biological factors may include increased penile sensitivity, serotonin imbalance, erectile dysfunction, prostate inflammation, or thyroid disorders. Many cases involve more than one factor.
What are the different types of premature ejaculation?
Lifelong (primary) PE is present from first sexual experiences. Acquired (secondary) PE develops after a period of normal function. Situational PE occurs only in certain circumstances, while generalized PE occurs in most sexual situations. Identifying the type helps guide treatment.
PE TREATMENT IN 3 STEPS
Three Simple Steps
Describe Your Symptoms
Share your symptoms or a brief description of your medical concern.
The next available provider will review your request and respond within minutes.
Virtual urologist consultation for Premature Ejaculation (PE) is completely FREE.
Chat with a Urologist
If the provider determines they can help, you’ll be connected for a consultation.
Most chats happen over text, but video or audio calls may be requested if necessary.
If we’re unable to assist, we’ll advise you to visit a walk-in clinic instead.
Receive Your Prescription in a Discreet Package
If PE treatment is appropriate, your prescription will be sent directly to your home in plain, unmarked packaging – at a time that works for you.
More about Premature Ejaculation
When should someone see a doctor?
Medical evaluation is recommended if ejaculation occurs sooner than desired most of the time, causes distress or relationship problems, develops suddenly, or is associated with erectile dysfunction or urinary symptoms. A healthcare provider can rule out underlying medical causes and recommend treatment options.
How is premature ejaculation diagnosed?
Diagnosis is based primarily on medical and sexual history. A physical examination may be performed, and laboratory tests may be ordered if hormonal or thyroid conditions are suspected. There is no single laboratory test that confirms PE.
What behavioral techniques help with premature ejaculation?
The start–stop technique involves pausing stimulation before ejaculation and resuming after the urge decreases. The squeeze technique applies pressure to reduce arousal just before climax. Pelvic floor (Kegel) exercises strengthen muscles that may improve control. These methods require practice and consistency.
Does psychological counseling help?
Yes. Counseling can address performance anxiety, stress, depression, or relationship concerns. Cognitive behavioral therapy and couples therapy may improve confidence, communication, and sexual satisfaction.
Can lifestyle changes improve symptoms?
In some cases, yes. Reducing stress, exercising regularly, limiting alcohol, avoiding recreational drugs, and managing erectile dysfunction can support overall sexual health and improve treatment outcomes.
How long do SSRIs take to work?
Daily SSRIs typically take one to three weeks to produce noticeable improvement, although some men may experience benefit sooner.
What are common side effects of SSRIs?
Possible side effects include nausea, fatigue, sweating, reduced libido, erectile difficulties, and mood changes. Effects vary between individuals, and medical monitoring is recommended.
Discreet, Personalized PE Care Backed by Urology Experts
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Clinical Associate Professor, Department of Urology
Mount Sinai – Department of Urology
Expertise: Bladder Cancer, Congenital Kidney Disease, Cystoscopy, Erectile Dysfunction, Fertility, Frequent Urination, Hydrocele/Varicocele
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Assistant Professor of Urology and Urologic Oncology, Icahn School of Medicine at Mount Sinai
Expertise: Adrenalectomy, Adrenocortical Carcinoma, Bladder Cancer, Cystectomy, Cystoscopy, Kidney Cancer, Kidney Stones, Laparoscopy, Nephrectomy, Prostate Biopsy, Prostate Cancer
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Urologist
University of Lille, Urology Department
Expertise: Prostate Cancer, Nephrectomy, Erectile Dysfunction, Prostatectomy, Benign Prostatic Hyperplasia, Orchiectomy, Paraphimosis, Hydronephrosis, Cystectomy, Endoscopy
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Professor, Urology
Institute for Regenerative Medicine
Wake Forest Baptist Medical Center
Expertise: Prostate Cancer, Kidney Cancer, Bladder Cancer, Enlarged Prostate, Penile Cancer
Ashok HemalMD, MCh, FACS, FRCS
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Professor of Urology, Vita-Salute University San Raffaele
Expertise: Prostate Cancer, Sexual Dysfunctions, Benign Prostatic Hyperplasia
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Katherine and Clifford Goldsmith Professor of Urology
Professor of Oncology
Mount Sinai – Department of Urology
Expertise: Prostate Cancer, Kidney Cancer, Cystoscopy, Benign Prostatic Hyperplasia, Bladder Cancer, Neurogenic Bladder, Frequent Urination
More about PE treatment
Are there topical treatments for premature ejaculation?
Yes. Numbing creams or sprays containing local anesthetics such as lidocaine or prilocaine reduce penile sensitivity and may delay ejaculation. They should be used carefully to prevent excessive numbness or transfer to a partner.
Can combining treatments improve results?
Yes. Many men benefit from combining medication with behavioral therapy. This approach may improve both short-term control and long-term outcomes.
Is it safe to self-medicate?
No. A healthcare provider should evaluate symptoms before starting treatment. Some medications interact with other prescriptions or may not be appropriate for certain medical conditions.
What is the outlook for men with premature ejaculation?
The prognosis is generally very good. With appropriate evaluation and treatment, most men experience meaningful improvement in control, sexual satisfaction, and relationship quality.
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